2 Timothy 4:3 For the time will come when they will not endure sound doctrine; but after their own lusts shall they heap to themselves teachers, having itching ears;
Sadly, this isn't solely a scripture about the world. Many of our own membership will not endure sound doctrine.
When someone in the church bristles at the simple statement that boys really are boys, or that girls really are girls, or that only boys and girls should be allowed to marry each other, then we have gone far beyond not enduring sound doctrine. At that point, we are not even enduring reality itself.